They're comparable but Clorox is far more versatile. Clorox also has disinfectant and sanitizing properties as well.

Clorox is better

Clorox is better for bathrooms and such.

These particular Clorox wipes are not intended for use as a floor wipe (although there is nothing wrong with doing that-- you'd likely need alot of them, though). The Swiffer wipes are specially designed for floor cleaning. So, I think that Clorox wipes are best for surfaces like countertops, tabletops, etc. Swiffer wipes are best for the floor. They are textured.